Troponin is a complex of three proteins (Troponin C, Troponin I and Troponin T) that regulate skeletal and cardiac muscle contraction. Cardiac Troponin I and T are sensitive and specific indicators of myocardial damage, and their blood levels rise in relation to the extent of injury to heart muscle from various conditions or from drug-induced cardiotoxicity. Cardiac troponins may be useful in predicting cardiovascular risk and mortality in the presence of chronic renal disease.
The Troponin I ELISA is a direct ELISA designed to measure circulating cardiac Troponin I in blood. It is for research purposes and is not intended for diagnostic use.